PCD PHARMA FRANCHISE BUSINESS OF CARDIOVASCULAR DRUGS
TYPES OF CARDIOVASCULAR DRUGS
Pulmonary Hypertension Drugs
Pulmonary hypertension is usually a result of narrowing of the small arteries of the lung. This makes hard for blood to flow and icreases blood pressure. The right side of the heart has to work hard to pump blood, and gets enlarged with time. Result may be failure of heart.
Despite the fact that there is currently no drug for pulmonary hypertension, there are drugs and treatments that can assist in decreasing the progression of this disease.
Pulmonary Hypertension Drugs:
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Vasopressors are drugs that constrict (narrows) blood vessels which increases the blood pressure. They are used in treating extremely low blood pressure, especially in patients critically ill.
- Dopamine Hcl
- Dobutamine Hcl
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An antiplatelet drug is a member of a class of pharmaceuticals that decrease platelet aggregation and inhibit thrombus formation. They are effective in the arterial circulation, where anticoagulant drugs do not affect much.
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Anticoagulants are medicines that help fight blood clotting. They are given to people who are at a high risk of developing clots, to reduce chances of developing more serious conditions like strokes and heart attacks.
A blood clot is a seal developed by the blood to stop bleeding from wounds. Although they are useful in stopping bleeding, they may block blood vessels and stop blood flow to organs such as the brain, heart, and lungs if clot develops in the wrong place.
Anticoagulants work by disrupting the process involved in the formation of blood clots. They are at times called “blood-thinning” medicines, although the fact is they actually do not make the blood thinner.
- Reviparin Sodium
- Tirofiban Hcl
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The drugs used in clotting and bleeding disorders can be divided into 2 major catagories:
- Drugs used to decrease clotting or it can dissolve clots already present in patients who are at risk for vascular occlusion
- Drugs used to increase clotting in patients with clotting deficiencies ( Blood unable to clot at all ).
The first group, the anticlotting drugs, includes some of the most commonly used drugs in the India. Anticlotting drugs are used for both treatment and prevention of myocardial infarction and other acute coronary syndromes, atrial fibrillation, ischemic stroke, and deep vein thrombosis (DVT).
The anticlotting group of drugs, the anticoagulant and thrombolytic drugs are effective in treatment of both venous ( clotting within veins ) and arterial thrombosis ( Clot that develops within artery )
- Vitamn K
- Tranexamic Acid
- Calcium Dobesilate
- Sodium tetradecyl
- Protamine Sulphate
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Peripheral Vasodilator drugs
Peripheral vasodilators are medicines that are prescribed in the treatment of various conditions that affect blood vessels in outer (peripheral) parts of the body such as the arms and legs.
Peripheral Vasodilator drugs:
- Ginko Biloba
- Cinnarizine with Domperidone
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Angina is chest pain or stiffness and it occurs when your heart muscle does not get the required amount of oxygen-rich blood. The pain usually starts with physical activity or stress and lasts for a few minutes (angina attack).
It may feel like pressure or squeeze in your chest. The discomfort may spread to your shoulders, arms, neck, jaw, or back. Angina pain might feel like indigestion. However, it’s not a disease. It is a symptom of an underlying heart problem and it is a symptom of coronary heart disease (CHD).
- Glyceryl Trinitrate
- Isosorbide Dinitrate
- Isosorbide 5 Mononitrate
- Atenolol and Nifedipine
- Atenolol & Nitrendipine
- Amlodipine & Atenolol
- Amlodipine & Enalapril
- Amlodipine & Enalapril
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Diuretics are a class of drugs commonly known as “water pills.”
They’re prescribed for treating high blood pressure; swelling of the feet, ankles, lower legs and fluid in the lungs caused by heart failure; fluid buildup in the abdomen caused by liver damage or certain cancers; and eye conditions such as glaucoma.
Other conditions that may be treated with diuretics include diabetes insipidus, polycystic ovarian syndrome (PCOS), kidney stones, male-pattern baldness in women, and osteoporosis.
The drugs reduce the amount of fluid in your blood vessels, and this helps lower your blood pressure. Diuretics are also used in chronic renal failure to treat edema due to nephrotic syndrome and congestive heart failure (CHF).
- Frusemide ( Furosemide )
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Blood pressure is the force of blood pushing against the artery walls as the heart pumps out blood into the arteries. Its level changes with age, sex, level of physical activity and psychological changes.
Hypertension refers to the sustained increase in blood pressure above the normal range. According to the World Health Organization, “hypertension” is defined as systolic/diastolic pressure persistently higher than 140/90mmHg. The risk for hypertension includes increasing age, family history, overweight, and smoking. At times, high blood pressure also be caused by certain medications or underlying diseases such as kidney or endocrine diseases.
- Enalapril Maleate
- Losartan Potassium
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Antiarrhythmics are used to treat heart rhythm disorders, called arrhythmias, and to reduce the symptoms associated with them. Some of the common symptoms of arrhythmias include
- Heart palpitations
- Irregular heartbeats
- Fast heartbeats
- Chest pain
- Shortness of breath.
Irregular heartbeats may be a congenital condition (since birth) or may develop if part of heart muscle tissue is damaged, which leads to disruption or “short circuit” in the heart’s electrical system. Antiarrhythmics work in a different way to reduce the electrical impulses in the heart which enures a regular rhythm.
Digoxin is another drug used as an antiarrhythmic, however, it is not included in this categories.
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Beta blockers or beta-adrenergic blocking agents, are branch of medications that reduce blood pressure. They work by blocking the effects of the hormone epinephrine, well known as adrenaline.
When you take beta blockers, your heart beats slowly and with less vigour, thereby reducing blood pressure. Beta blockers also help blood vessels opening up which improves blood flow.
Beta blockers mainly affect your heart, although some affect both your heart and your blood vessels. Type of drug doctor prescribes you depends upon once health and the physical condition to be treated.
Beta Blockers Drugs:
- Propranolol and Alprazolam
- Atenolol with Indapamide
- Atenolol with Losartan
- Phentolamine Mesylate
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Cardiac Glycosides drugs
Cardiac glycosides are medicines for treating heart failure and certain irregular heartbeats. They belong to one of several classes of drugs prescribed to treat heart and related conditions.
Cardiac glycosides work by acting on the cell membranes of heart. They increase the contraction or pumping strength of the heart. This result in heart pumping more blood per beat through the body.
Cardiac glycosides are found in some plants, including the leaves of the digitalis (foxglove) plant and it is the original source of this medicine.
Cardiac Glycosides Drugs: